Apache2 Python error, initfsencoding

Doing a little bit of reading on the topic, it looks like that error most commonly stems from a misconfiguration of either the Python Shared Library or the Python Environment. You might find the following links helpful.

https://stackoverflow.com/questions/46759730/django-mod-wsgi-fatal-python-error-py-initialize-no-module-named-encodings

https://stackoverflow.com/questions/38132755/importerror-no-module-named-encodings

If those don't help you find the solution you are looking for I would recommend providing the httpd.conf block from your Apache configuration as well as the Python env output. This can help to gather more information and locate a more specific source of the issue.